CPPD disease


  • Rare before age 30; increased incidence in the elderly (27% to 50% in ages 85 to 90).
  • Usually polyarticular, 2/3 is symmetricall
  • Diagnosis is made by joint aspiration.
  • Treated with nonsteroidal anti-inflammatory drugs (NSAIDs), joint injection, corticosteroids, or colchicine.


  • Chondrocalcinosis is not required for diagnosis
  • commonly involves non-weight bearing joints
    Knee > > wrist > hand > shoulder, hip, elbow
  • Knee: commonly involves patellofemoral joint
  • Hand: 2nd and 3rd MCP, hook like osteophytes
  • Wrist: radiocarpal and scapholunate joint; scapholunate advanced collapse can be seen in severe cases
  • Geodes and erosion are common

Hook like osteophyte with radiocarpal joint subluxation
Hook like osteophyte in CT

Perilunate dislocation

SLAC (scapholunate advanced collapse): a gap can be seen between scapholunate joint

Reference: auntieminnie, radiopaedia.org


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